A study of column equilibration time in hydrophilic interaction chromatography
نویسندگان
چکیده
منابع مشابه
Hydrophilic interaction chromatography
In the early 1990s, hydrophilic interaction (liquid) chromatography (HILIC) emerged as a new separation method. HILIC is becoming increasingly popular for the separation of polar compounds in aqueous-organic mobile phases rich in organic solvents (usually acetonitrile). It has become important for the separation of pharmaceuticals, neurotransmitters, nucleosides, nucleotides and other compounds...
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متن کاملSeparation Mechanisms in Hydrophilic Interaction Chromatography
Hydrophilic interaction chromatography (HILIC) is a technique that has become increasingly popular for the separation of polar, hydrophilic, and ionizable compounds, which are diffi cult to separate by reversed phase chromatography (RP) due to their poor retention when RP is used. HILIC typically uses a polar stationary phase such as bare silica or a polar bonded phase, together with an eluent ...
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ژورنال
عنوان ژورنال: Journal of Chromatography A
سال: 2018
ISSN: 0021-9673
DOI: 10.1016/j.chroma.2018.04.016